“You are worthy, our Lord and God,
    to receive glory and honor and power,
for you created all things,
    and by your will they were created
    and have their being.”                                             Revelation 4:8, 11

The first phrase of this praise to God comes unceasingly, day and night, from four living creatures who are within and around His throne in heaven.  Holy is an attribution to God that He is totally other than anyone or any thing in all creation.  There is no one like Him in heaven or on earth.  A feeling that is similar to what might provoke us to say Holy would be our uncontrollable gasp in awe when we first step up to its edge and look into the Grand Canyon.  Lord let me daily approach You with such appropriate awe!

God simply identifies this totally overarching Being as Him from whom all things were created and to whom all things are due.  Lord conveys a more personal relationship of King/subject or Father/son, implying ownership, caring, and responsibility for the well-being of the lesser party.  That this personal Lord God is also Almighty is comforting and reassuring, since He dedicates Himself to our well-being.  Were He not also our caring Lord, His infinite power would be terribly frightening.  The four living creatures attribute to this Lord they worship that He has always existed and always will.  He is the only self-existant One.  He will make things right, and He will always be there to keep them right.

The next verse (11) is voiced by His believing human creation, the 24 elders, now translated into heaven.  They honor their Lord by casting before Him the crowns awarded to them.  These 24 elders praise Him for His power and His sovereignty, for He creates anything He wills into being by simply willing it to be. 

O give me a heart that approaches You with appropriate humility and contrition, acknowledging Your infinite majesty and control over the universe and my total dependence on You to order every detail of my life.